ISSN: 2795-3637
EISSN: 2795-3580
Published: 2022-12-05
Nigeria has some of the most disturbing health indicators in sub Saharan Africa and indeed the world. The WHO estimates that about 157 out of 1000 Nigerian children annually die before their fifth birthdays, from preventable/treatable diseases. This is aside the fact that Nigeria contributes about 10% of global maternal mortality though it hosts just 2% of the world female population. This narrati
The HIV pandemic has greatly contributed to the emergence of opportunistic fungal infections. Over the last two decades Cryptococcus neoformans infection is estimated to cause more than 500,000 deaths annually among HIV positive subjects in sub-Saharan Africa. However, in this environment scant attention has been paid to the screening of this infection. This study was therefore designed to determi
Parallel evolution involving historically independent amino acid substitutions in hemoglobin (Hb) is expected among closely related lineages; however, such studies in distantly related species are limited especially from the structural point of view. Here we reported structural and phylogenetic based parallel amino acid substitutions in the βA globin gene of the Black kite (BK), Bar-headed goose (
Cerebral Malaria (CM), a highly lethal form of severe malaria is known to cause inflammation that exacerbates pathology in the brain predominantly due to inflammatory immune response as a result of Plasmodium falciparum infection. There is limited progress in the development of new approaches for the treatment of CM. Therefore, in this study we investigated whether oral Ubidercarenone (Ubn) can re